Buy AM-1241 Online (100g)

$530.00 $520.00

 AM1241 exhibits high affinity and selectivity for CB2 receptors. It also exhibits high potency in vivo. We designed AM1241, a selective CB2 cannabinoid receptor agonist, and used it to test the hypothesis that CB2 receptor activation would reverse the sensory hypersensitivity observed in neuropathic pain states. AM1241 dose-dependently reversed tactile and thermal hypersensitivity produced by ligation of the L5 and L6 spinal nerves in rats. These effects were selectively antagonized by a CB2 but not by a CB1 receptor antagonist, suggesting that they were produced by actions of AM1241 at CB2 receptors.

IUPAC  name:  (3-iodo-5-nitrophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone
Other  name:  1-(methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole
CAS number:     444912-48-5
Formula:        C22H22IN3O3
Purity:  99,9% min
Appearance:  white powder
AM-1241 is a chemical for research purposes and should only be used for this purpose. AM-2201 is not sold for human consumption.